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Agenda

08:15-08:45

Registration

Opening Remarks and Group Photo

08:45-09:00

Jane C-J Chao   (Dean, Office of Global Engagement, TMU)

Wei-Chiao Chang (Dean, TMU)

09:00-09:05

Group photo

Session 1 : Analytical Chemistry and Pharmaceutics

Chair : Sung-Bau Lee

09:05-09:25

Mass spectrometric studies on tyrosine-modified insulin-degrading enzyme: Altered substrate specificity and its relevance in Alzheimer’s disease and type 2 diabetes mellitus

Yusuke Hatakawa (Graduate School of Pharmaceutical Sciences, Tohoku University)

09:25-09:45

Development of fluorescent nucleobase analogs for the detection of oxidized nucleobases and DNA higher-order structures

Yasufumi Fuchi (Department of Pharmaceutical Sciences, Graduate School of Biomedical Sciences, Nagasaki University)

09:45-10:05

Enantioselective Analysis of Lactate and Amino Acids within the Colorectal Cancer Metabolic Microenvironment

Jen-Ai Lee (College of Pharmacy, Taipei Medical University)

Session 2 : Natural Products and Medicinal Chemistry

Chair : Yi-Min Liu

10:10-10:30

Total Synthesis of Sulfur-Containing Complex Natural Products

Juri Sakata (Graduate School of Pharmaceutical Sciences, Tohoku University)

10:30-10:50

Radiolabeling strategy for middle-sized bioactive molecules with short-lived PET nuclides

Takashi Niwa (Laboratory of Molecular Transformation Chemistry, Graduate School of Pharmaceutical Sciences, Kyushu University)

10:50-11:10

Pragmatically designed Dual SYK–HDAC Inhibitors as Potent Antileukemic Chemotypes for Acute Myeloid Leukemia

Kunal Nepali (School of Pharmacy, Taipei Medical University)

11:10-11:20

Tea/Coffee Break

Student Session 1 : Analytical Chemistry and Pharmaceutics &

Natural Products and Medicinal Chemistry

Chairs: Juri Sakata, Shunsuke Nashimoto

11:20-12:20

Tumor cell-derived extracellular vesicle surface proteins as biomarker-guided therapies for the treatment of pancreatic ductal adenocarcinoma

Wei-Ni Tsai (National Yang Ming Chiao Tung University)

Rapid D2B Screening Platform for PROTACs Using a Solid-Phase Library

Ayano Ito (Tohoku University)

Bioactive Terpenoids with a 4/9-Fused Ring System from Sclerophytum humesi: Structural Diversity, Multitarget Inhibitory Potential, and Biosynthetic Perspectives

Phuong Vu Luu (Taipei Medical University)

A New Photoinduced Method for Aryne Generation from Triazenes

Taiju Tanaka (Kyushu University)

Development of data-independent acquisition mass spectrometry strategy for characterization of heterogeneous immune cell populations

Morgan Kamanga (Taipei Medical University)

The multifaceted potentials of HSP90/LSD1 dual inhibitors

Chen-Ping Chou (Taipei Medical University)

12:20-13:30

Lunch Break / Committee Meeting

Student Session 2 : Clinical Pharmacy & Molecular Precision Pharmacy

Chairs:  Yuta Kohro ,  Koji Matsuhisa

13:30-14:40

Cost-related Medication Nonadherence among U.S. Pregnant Women: findings from 2011 to 2024 National Health Interview Surveys

Chloe Chen (National Yang Ming Chiao Tung University)

The amygdala, a fear-related brain region, directly controls heart rate

Misha Kushiro (Tohoku University)

Proteomic analysis using LC-HRMS to compare intracellular protein expression in bone marrow-derived mesenchymal stromal cells

Kaede Nakajima (Hokkaido University)

Establishment of inter-charge spacing model for optimization of salt concentration during ionic polymer/plasmid DNA complex formation

Moe Nakashima (Nagasaki University)

Chrono-immunotherapy based on the circadian rhythm of CTLA4 expression in tumor-infiltrated regulatory T cells (Tregs)

Wen-Yu Chen (Kyushu University)

Impaired skin barrier formation and ceramide composition changes in mouse models of atopic dermatitis and psoriasis

Nana Nozaka (Hokkaido University)

Focused Ultrasound-Mediated Brain Delivery of IL-12 mRNA-LNPs for Glioblastoma Therapy 

Riku Takayama (Nagasaki University)

Session 3 : Clinical Pharmacy

Chair :   Elizabeth H. Chang

14:40-15:00

Development of Dosage Regimens for Antifungal Agents Based on the Albumin–Bilirubin Score

Shunsuke Nashimoto (Faculty of Pharmaceutical Sciences, Hokkaido University)

15:00-15:20

Role of a population of spinal astrocytes in somatosensory processing

Yuta Kohro (Department of Pathophysiology, Graduate School of Pharmaceutical Sciences, Kyushu University)

15:20-15:40

Expanding the Ubiquitin Ligase Toolbox for Targeted Protein Degradation

Koji Matsuhisa (Department of Pharmacology and Therapeutic Innovation, Graduate School of Biomedical Sciences, Nagasaki University)

15:40-15:50

Tea/Coffee Break

Session 4 : Molecular Precision Pharmacy

Chair : Mei-Chuan Chen  

15:50-16:10

Targeted Polysaccharide Nanoparticles for pH-Responsive Drug Release in Cancer Therapy

Yu-Hsin Lin (Department of Pharmacy, College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University)

16:10-16:30

Toward Organelle Medicine through Mitochondria-Targeted Nanocapsules

Yuma Yamada (Faculty of Pharmaceutical Sciences, Hokkaido University)

16:30-16:50

New Approach Methodologies (NAMs) for the Safety Assessment of Emerging Chemicals: A Case Study of Bisphenols

Yi-Jun Lin (Institute of Food Safety and Health Risk Assessment/College of Pharmaceutical Sciences, National Yang Ming Chiao Tung University)

Announcement for Next Meeting

16:50-17:00

Satoru Koyanagi, Dean, Kyushu University

Closing Remarks

17:00-17:10

Hsiang-Yin Chen, Associate Dean, Taipei Medical University